Research project title

Conditional economic incentives and motivational interviewing to improve adolescents’ retention and adherence to antiretroviral therapy and care in south-east Nigeria: a cluster-randomized trial

Funder: EDCTP and EU

Research investigator

Dr Obinna Ekwunife

Address & contact details of the research investigator

Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, Agulu Campus, Nnamdi Azikiwe University, Awka

Other researchers involved in this project

About the Project

Some adolescents attending antiretroviral (ARV) treatment hospitals have poor attendance record and low adherence to medications. This situation does not help their wellbeing and the health of the whole population. Therefore we want to explore whether an ‘Incentive Scheme’ comprising of cash gift conditioned on meeting a set goal coupled with motivational interviewing could be used to improve retention in care and adherence to antiretroviral medication. We will randomise ARV treatment hospitals in this study into two groups. One group will receive the incentive scheme and the other will receive the usual care.

Who is responsible for the data collected in this study?

The following are the researchers involved in this project as well as their roles:

Researcher Role
Dr Uchenna Eleje Supervisor for the study
Dr Obinna Ekwunife Principal investigator
Mrs Maureen Anetoh Research Assistant I (field and operations)
Mr Stephen Kalu Research Assistant II (laboratory)

Data to be collected as well as methods used for collecting this information are as follows:

Data Method of collection
Demographic data without name identifier Patient folder and interview
Clinical data without name identifier Patient folder
Blood samples Needle and syringe

Demographic and clinical data will be stored in a passworded database and deleted after 5 years. All blood samples will be destroyed at the end of the study. All information and blood samples collected in this study will be given code numbers and no name will be recorded. This cannot be linked to you in any way and your name or any identifier will not be used in any publication or reports from this study. None of these data will be shared with any other person or institution apart from the participating ARV treatment hospitals and the investigators. This study will be reviewed by Nnamdi Azikiwe University Teaching Hospital.

What is involved in the study?

Once every three months, you will have a chat with health personnel and then your blood sample will be collected. This should not take more 1 hour. The total study period is 2 years.

What are the risks involved in this study?

We do not foresee any risk that could arise from this study. As far as possible your contribution will be kept confidential.

What are the benefits of taking part in this study?

All the study participants will receive proper monitoring and prompt treatment. You can win a cash gift of NGN 1000 to NGN 2000 for achieving treatment goal if incentive scheme applies to your hospital. The final result will be published in a scientific journal. Also, the findings can be explained to you if you call Dr Obinna Ekwunife using 07062032501. Taking part in the study is voluntary. You may choose not to take part or subsequently cease participation at any time.

Will I receive any payment or monetary benefits?

You will receive no payment for your participation. The data will not be used by any member of the project team for commercial purposes. Therefore you should not expect any royalties or payments from the research project in the future.

For more information

This research has been reviewed and approved by the Nnamdi Azikiwe University Ethics Committee. If you have any further questions or concerns about this study, please contact: Dr Obinna Ekwunife, 07062032501, oi.ekwunife@unizik.edu.ng

You can also contact Dr George Eleje (Supervisor), 08068117444, gu.eleje@unizik.edu.ng

What if I have concerns about this research?

If you are worried about this research, or if you are concerned about how it is being conducted, you can contact the Chair of the Nnamdi Azikiwe University Teaching Hospital Ethics Committee. The number of the secretary is: 07032792205